Why this happens
Estradiol supports serotonin synthesis, receptor sensitivity and BDNF. Progesterone metabolites calm GABA. When these fluctuate, mood circuits destabilise — even in women with no prior depression.
Mood & Hormones
Low mood in perimenopause.
New onset depression in your 40s, especially around your cycle, is often hormonal. Estradiol modulates serotonin directly. Many women avoid years of trial-and-error SSRIs once hormones are addressed.
Serving Lowell, Fayetteville, Rogers, Bentonville, Springdale & Bella Vista — Northwest Arkansas
- Mood lifts
- Motivation returns
- Less crying
- Stable cycle moods
- Energy back
- Better relationships
Our approach
Full hormone panel, thyroid, B12 and vitamin D. BHRT, progesterone at night, thyroid optimisation, exercise, and SSRIs only when truly indicated — coordinated with your prescriber.
FAQ
Frequently asked questions.
+Should I stop my SSRI?
Never abruptly. Many patients taper successfully once hormones are dialled in — with their prescriber's help.
+How fast does this work?
Most women feel a real shift in 4–8 weeks.
Ready to feel like yourself again?
Book a one-on-one consultation with Dr. Tammy and get a personalized plan built around your labs, symptoms, and goals.
Questions? Get in touch.
Our staff would love to help you choose the service that's right for you.
Prefer texting? You can text us at 479-715-3928.